Abstract: Regulations in the EU and the US
authorize the use of migration modeling to demonstrate the compliance of food
contact materials or substances. The legal basis assumes that there is enough
scientific evidences to support compliance but not for non-compliance. This
presentation will give an overview of the different recognized methods to
overestimate the migration in food and consumer exposure. In simple cases, the
overestimation can originate from conservative assumptions or from
probabilistic estimates. For more sophisticated cases involving complex designs
or industrial practices along the supply chain, more robust approaches are
required. A recent methodology based on Failure Mode and Effects and Critical Analysis will be illustrated as well as the concepts of food
packaging “safe-by-design”. http://modmol.agroparistech.fr/SFPD/
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